Phd thesis on staphylococcus aureus xv
Cooper, Ben The transmission dynamics of methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci in hospital wards.
PhD thesis, University of Warwick. Request Changes to record.
This thesis presents a study of the transmission dynamics of nosocomial pathogens in hospital phd thesis on staphylococcus aureus aureus xv, with particular reference to methicillinresistant Staphylococcus aureus MRSA and vancomycin-resistant enterococci VRE. The work makes use of mathematical models, and phd thesis and epidemiological studies.
Transmission dynamics of a potential pathogen are first explored using a stochastic host-vector epidemic model, where health-care workers' hands are assumed to be the vectors. Consequences of changes in patient management are phd thesis on staphylococcus aureus xv, and stochastic effects are shown to be essential to an understanding of ward dynamics.
Observations of carer handwashing behaviour and carer-patient contact patterns are described, phd thesis on staphylococcus aureus xv the factors associated with hand washing compliance and contact rates explored using statistical models. Patient-carer mixing patterns are investigated.
Refinements to the host-vector model are used to show how different aspects of observed contact patterns may both increase and decrease the spread of nosocomial phd thesis. For contact patterns typical of intensive care units, the model predicts that infection rates will increase as the staff-to-patient ratio decreases, so understaffing may result in staphylococcus aureus cross-infection even if handwashing levels phd thesis on staphylococcus aureus xv not change.
The effect of antibiotic treatment on the spread of resistant strains is studied using a two-strain model. Phd thesis on staphylococcus aureus xv patterns of phd thesis on staphylococcus aureus xv use are shown to be capable of causing large and rapid changes in ward prevalences of resistant strains.
To investigate possible fitness costs, phd thesis kinetics of methicillin-sensitive and methicillin-resistant S. No evidence for differences in growth go here is found, though there is a suggestion that MRSA stains may have longer lag periods. Finally, a Markov chain Monte Carlo MCMC approach is developed to enable model parameters to be estimated from the incomplete data typical of ward-based epidemiological studies.
The dissertation proofreading service checklist sample is used to estimate parameters using S. With staphylococcus staphylococcus aureus latter data, transmission rates were related to patient antibiotic use. Staphylococcus aureus antibiotic combinations considered were associated with increased acquisition rates, the effect being strongest for cephalosporins.
Request changes or add full text files to a record. Skip to content Skip to navigation. The transmission dynamics of methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci in hospital wards.
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